Obstructive sleep apnoea (OSA) is common and drives daytime sleepiness, cognitive impairment, and cardiometabolic risk. Positive airway pressure is first-line therapy. With modern auto-adjusting CPAP (APAP), appropriately selected adults can start therapy safely in primary care with outcomes comparable to specialist pathways when follow-up is structured (Patil et al., 2019). This guide covers candidate selection, starting settings, first-month review, troubleshooting, and escalation.
1) Who benefits most from Auto-CPAP vs Fixed CPAP
Guideline position. The 2019 AASM guideline strongly supports initiating PAP with home APAP or in-lab titration for adults with uncomplicated OSA; both APAP and fixed CPAP are acceptable long-term (Patil et al., 2019).
Why APAP first:
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Automatically adapts to night-to-night and weight-related pressure variation.
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Enables immediate start without in-lab titration.
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Adherence and sleepiness outcomes comparable to lab titration and fixed CPAP.
When fixed CPAP may suit better:
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Stable effective pressure identified after an APAP trial.
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Patient prefers a single set pressure.
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Payer criteria require fixed CPAP.
Not for primary-care APAP start (refer/escalate):
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Chronic respiratory failure, hypoventilation, advanced COPD
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CHF with Cheyne–Stokes respiration
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Neuromuscular ventilatory disorders
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Central or complex sleep apnoea
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Severe hypoxaemia, unstable CVD, opioid-related apnoeas
2) Initial APAP settings: pressure, ramp, EPR
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Pressure range: Start 4–12 cm H₂O (conservative, guideline-aligned for unattended APAP).
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Ramp: Enable for comfort; begin low (≈4 cm H₂O) and rise gradually.
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EPR (expiratory relief): Use if expiratory discomfort or with nasal masks.
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Humidification: Recommend from day one to improve tolerance.
3) First 30 days: what to review and when to escalate
Early review prevents abandonment.
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Usage: Target ≥4 h/night on ≥70% of nights. Suboptimal use → address comfort, education, side-effects.
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Leak: Keep unintentional leak low. Refit/adjust headgear; change mask category if persistent.
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Residual AHI: Aim ≤5/h. Higher values suggest pressure loss, REM/positional clustering, or inadequate settings.
Escalate (sleep specialist or in-lab titration/CPAP Adelaide support) if:
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Persistent poor tolerance despite comfort tweaks
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High leak unresponsive to interface changes
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Elevated residual AHI within current range or symptoms not improving
4) Managing common side-effects
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Rhinitis/congestion: Heated humidification; consider intranasal corticosteroid.
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Dryness/irritation: Increase humidifier heat incrementally.
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Mouth leak: Switch to full-face mask or add chin strap; reassess fit.
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Aerophagia: Slightly lower minimum pressure if feasible; extend ramp; coach swallowing/neutral neck.
5) A practical GP workflow
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Confirm uncomplicated OSA; exclude contraindications.
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Prescribe APAP 4–12 cm H₂O with ramp ± EPR; choose interface appropriate to breathing pattern.
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Educate on device use, goals (usage/leak/AHI), and how to reach CPAP Adelaide for support.
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Review at ~30 days (or sooner if issues).
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Troubleshoot; escalate to CPAP Adelaide or specialist/PSG if efficacy or tolerance remain suboptimal.
Conclusion
APAP enables GPs to initiate effective OSA therapy in suitable adults using a simple range (4–12 cm H₂O), early comfort features, and focused 30-day review of usage, leak, and residual AHI. Proactive side-effect management reduces dropout, while clear escalation pathways via CPAP Adelaide and sleep specialists maintain safety and outcomes aligned with best-practice guidelines.
References
- Patil SP, Ayappa IA, Caples SM, Kimoff RJ, Patel SR, Harrod CG. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019 Feb 15;15(2):335–343. DOI: 10.5664/jcsm.7640. PMID: 30736887.
- AASM guideline highlights the importance of follow-up, usage monitoring, and troubleshooting early in therapy (pmc.ncbi.nlm.nih.gov)
- APAP efficacy equivalence with PSG titration in adherence and sleepiness outcomes (jcsm.aasm.org).
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AASM practice parameters support unattended APAP use within defined pressure ranges (aasm.org, pmc.ncbi.nlm.nih.gov).